The Research Unit on Bioactive Molecules (RUBAM) offers internships for graduate Students in Chemistry, Biology, Biomedicine, and related matters. We offer two different lines of research, depending on the candidate formation.
1) Synthesis, purification and characterization of labelled or labelable molecules by click chemistry. These probes will be used within the frame of our current research projects related to sphingolipid localization and trafficking and proteasomal labelling in life cells. The internship will become familiar with the daily work in an organic synthesis lab, as well as in the use of the required purification and analytical techniques (MPLC, UPLC, NMR, etc) for the proper characterization of the synthesized compound.
2) Cell viability and cell labelling studies of our “in house” developed probes. The internship will acquire experimental skills in the common general tasks of a cell culture laboratory under the training and the supervision of specialized staff. In addition, an active participation of the candidate in the required cellular studies by fluorescence microscopy will be essential. They include, inter alia, the co-localization analysis of our probes in the presence of selective cell markers. This part of the training will be carried out in the confocal microscopy laboratory, also under the guidance of specialized staff members.